Osthole Promotes Endochondral Ossification and Accelerates Fracture Healing in Mice
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چکیده
منابع مشابه
Hyperbaric Hyperoxia Accelerates Fracture Healing in Mice
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Osthole is a bioactive coumarin derivative and has been reported to be able to enhance bone formation and improve fracture healing. However, the molecular mechanism of Osthole in bone fracture healing has not been fully defined. In this study we determined if Osthole enhances bone fracture healing through activation of BMP2 signaling in mice. We performed unilateral open transverse tibial fract...
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Bone fracture healing is a complicated physiological regenerative process initiated in response to injury and is similar to bone development. To demonstrate whether an exogenous supply of parathyroid hormone-related protein (PTHrP) helps in bone fracture healing, closed mid-diaphyseal femur fractures were created and stabilized with intramedullary pins in eight-week-old wild-type (WT) PTHrP+/+ ...
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ژورنال
عنوان ژورنال: Calcified Tissue International
سال: 2016
ISSN: 0171-967X,1432-0827
DOI: 10.1007/s00223-016-0189-4